北京市医疗机构抗菌药物临床应用分级管理目录的循证制订

doi:10.11669/cpj.2023.02.014

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中国药学杂志 ›› 2023, Vol. 58 ›› Issue (2) : 188-194. DOI: 10.11669/cpj.2023.02.014

论著

北京市医疗机构抗菌药物临床应用分级管理目录的循证制订

徐晓涵^1a,2,3, 周鹏翔^1a,2,3, 孔旭东⁴, 曹照龙⁵, 程吟楚^1a,2,3, 谷丽⁶, 海沙尔江·吾守尔^7,8, 贺蓓^1b, 胡欣^3,9, 刘朝晖¹⁰, 刘清华¹¹, 马小军^12a, 马序竹¹³, 齐文杰^14a, 苏建荣^14b, 王睿¹⁵, 王晓玲¹⁶, 徐英春^12b, 闫盈盈^1a,2,3, 杨旸¹¹, 应颖秋^1a,3, 翟所迪^1a,2,3, 赵志刚^3,17, 甄健存^3,18, 周颖^19a, 朱光发²⁰, 郑波^3,19b*, 杨毅恒^1a,2,3*

作者信息 +

Evidence-Based Formulation of Antibiotics Classification Management Lists in Beijing Medical Institutions

XU Xiao-han^1a,2,3, ZHOU Peng-xiang^1a,2,3, KONG Xu-dong⁴, CAO Zhao-long⁵, CHENG Yin-chu^1a,2,3, GU Li⁶, Haishaerjiang·Wushouer^{7, 8}, HE Bei^1b, HU Xin^3,9, LIU Chao-hui¹⁰, LIU Qing-hua¹¹, MA Xiao-jun^12a, MA Xu-zhu¹³, QI Wen-jie^14a, SU Jian-rong^14b, WANG Rui¹⁵, WANG Xiao-ling¹⁶, XU Ying-chun^12b, YAN Ying-ying^1a,2,3, YANG Yang¹¹, YING Ying-qiu^1a,3, ZHAI Suo-di^1a,2,3, ZHAO Zhi-gang^3,17, ZHEN Jian-cun^3,18, ZHOU Ying^19a, ZHU Guang-fa²⁰, ZHENG Bo^3,19b*, YANG Yi-heng^1a,2,3*

Author information +

1. a. Department of Pharmacy, b. Department of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Beijing 100191, China;
2. Beijing Pharmacy Center for Quality Control and Improvement, Beijing 100191, China;
3. Institute for Drug Evaluation, Peking University Health Science Center, Beijing 100191, China;
4. Department of Pharmacy, China-Japan Friendship Hospital, Beijing 100029, China;
5. Department of Respiratory and Critical Care Medicine, Peking University People's Hospital, Beijing 100044, China;
6. Department of Infection Diseases and Clinical Microbiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China;
7. School of Pharmaceutical Sciences, Peking University, Beijing 100191, China;
8. International Research Center for Medicinal Administration, Peking University, Beijing 100191, China;
9. Department of Pharmacy, Beijing Hospital, Beijing 100730, China;
10. Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing Maternal and Child Health Care Hospital, Beijing 100026, China;
11. Department of Pharmacy and Medical Equipment, Beijing Municipal Health Commission, Beijing 100053, China;
12. a. Department of Infectious Medicine, b. Department of Clinical Laboratory, Peking Union Medical College Hospital, Beijing 100730, China;
13. Department of Infectious Disease, Beijing Tsinghua Changgung Hospital, Tsinghua University, Beijing 102218, China;
14. a. Department of Infectious Medicine, b. Clinical Laboratory Center, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China;
15. Room of Medicine Clinical Research, Department of Pharmacy, Centre of Medical Security, Chinese People's Liberation Army General Hospital, Beijing 100853, China;
16. Department of Pharmacy, Beijing Children's Hospital, Capital Medical University, Beijing 100045, China;
17. Department of Pharmacy, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China;
18. Department of Pharmacy, Beijing Jishuitan Hospital, Beijing 100035, China;
19. a. Department of Pharmacy, b. Institute of Clinical Pharmacology, Peking University First Hospital, Beijing 100034, China;
20. Department of Respiratory and Critical Care Medicine, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China

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文章历史 +

摘要

目的探索建立基于循证医学的药品目录遴选方法,并修订北京市医疗机构抗菌药物临床使用分级管理目录,为科学形成药品目录和合理应用抗菌药物提供支持。方法北京市卫生健康委员会建立多学科的目录工作组根据目录计划书,整合药品数据、药品证据和专家意见,按照纳入排除标准,通过德尔菲法对北京市医疗机构抗菌药物临床使用分级管理目录形成专家共识。结果遴选的目录共纳入99种药品,与上版目录相比,新增10种抗菌药物,调出38种抗菌药物;另有5种和13种抗菌药物分别上调和下调了管理级别。结论以循证医学思想和方法为指导,通过全面的证据和数据支持、结合多学科专家的经验、科学的共识方法,可以提高药品目录修订的科学性和合理性。

Abstract

OBJECTIVE To explore the establishment of drug list selection method based on evidence-based medicine, and to revise the Antibiotics Classification Management Lists in Beijing Medical Institutions, so as to provide supports for the scientific formation of drug lists and the rational application of antibiotics. METHODS The Beijing Municipal Health Commission established a multidisciplinary drug list working group to integrate drug data, drug evidence and expert opinions based on the plan of drug list, and to form expert consensus on the classification management list through the Delphi method according to the inclusion and exclusion criteria. RESULTS A total of 99 kinds of drugs were included in the selected classification management list. Compared with the previous classification management list, 10 kinds of antibacterial drugs were added, and 38 kinds of antibacterial drugs were called out. Except that 5 kinds of antibacterial drugs were raised in management level, 13 kinds of antibacterial drugs were downgraded in management level. CONCLUSION Guided by the thought and methods of evidence-based medicine, through comprehensive evidence and data support, combined with the experience of multidisciplinary experts, and scientific consensus methods, the scientificity and rationality of the revision of the drug list can be improved.

导出引用

徐晓涵, 周鹏翔, 孔旭东, 曹照龙, 程吟楚, 谷丽, 海沙尔江·吾守尔, 贺蓓, 胡欣, 刘朝晖, 刘清华, 马小军, 马序竹, 齐文杰, 苏建荣, 王睿, 王晓玲, 徐英春, 闫盈盈, 杨旸, 应颖秋, 翟所迪, 赵志刚, 甄健存, 周颖, 朱光发, 郑波, 杨毅恒. 北京市医疗机构抗菌药物临床应用分级管理目录的循证制订[J]. 中国药学杂志, 2023, 58(2): 188-194 https://doi.org/10.11669/cpj.2023.02.014

XU Xiao-han, ZHOU Peng-xiang, KONG Xu-dong, CAO Zhao-long, CHENG Yin-chu, GU Li, Haishaerjiang·Wushouer, HE Bei, HU Xin, LIU Chao-hui, LIU Qing-hua, MA Xiao-jun, MA Xu-zhu, QI Wen-jie, SU Jian-rong, WANG Rui, WANG Xiao-ling, XU Ying-chun, YAN Ying-ying, YANG Yang, YING Ying-qiu, ZHAI Suo-di, ZHAO Zhi-gang, ZHEN Jian-cun, ZHOU Ying, ZHU Guang-fa, ZHENG Bo, YANG Yi-heng. Evidence-Based Formulation of Antibiotics Classification Management Lists in Beijing Medical Institutions[J]. Chinese Pharmaceutical Journal, 2023, 58(2): 188-194 https://doi.org/10.11669/cpj.2023.02.014

中图分类号： R95

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2022-06-13	2023-01-22
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2023-02-06

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